systemically

From systemic + -ally.

systemically (comparative more systemically, superlative most systemically)

1. In a systemic manner.
2. In a manner that affects an entire system.
   • 2015 July 25, “Anticancer Activity of Apaziquone in Oral Cancer Cells and Xenograft Model: Implications for Oral Cancer Therapy”, in PLOS ONE‎^[1], →DOI:

     Puri et al demonstrated that intravesically administered apaziquone is well tolerated locally and systemically, and it has ablative activity for superficial bladder cancer marker lesions.